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investigated the effects of CD38 deficiency and inhibition, as well as NAD supplementation, on lipopolysaccharide (LPS)-induced neuroinflammation in mice

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To address these challenges, various delivery methods have been investigated, including viral vectors, non-viral vectors, and rational design strategies such as chemical modifications, cationic liposomes, polymers, nanocarriers, and biocoupled siRNAs, aimed at enhancing stability and intracellular delivery (Yu et al., 2020)