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Consequently, optimisation of nose-to-brain delivery is frequently achieved through a combination of targeted deposition in upper nasal regions and permeability-enhancing excipients as well as nanocarrier systems that protect the active pharmaceutical ingredient (API) from enzymatic degradation and facilitate mucosal transport (Chung et al., 2023, Dhuria et al., 2010, Illum, 2003)

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Umbrella Labs intends to support these decisions with assay aware documentation that helps labs plan experiments with clearer interpretation in mind