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Because of the two free carboxylic acids and the free primary amine, Epithalon is a useful reference standard for reversed-phase separations, ion-pair chromatography, and calibration of low-molecular-weight peptide assays

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Additionally, ROS release activates the mPTP, causing Ca² + release and endoplasmic reticulum (ER) stress-induced autophagy-dependent ferroptosis (154)