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In LRRK2 knockdown murine microglia, LPS treatment reduces TNF-α, inducible nitric oxide synthase, IL-1β, and IL-6 mRNA and/or protein levels, indicating LRRK2 positively regulates inflammatory induction (193)

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The transformation of ascorbic acid (AH 2 ) either dissolved in tap water or in ultra-pure water is depicted as function of time in Figure 2