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Comment: A commenter shared their concern that none of the proposed measures in the ASM heart failure measure set are PRO-PMs, noting that two of the heart failure quality measures, Beta Blocker Therapy for LVSD and ACE/ARB/ARNI for LVSD, only apply to patients with reduced ejection fraction while the cost measures include patients with preserved ejection fraction

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This enzyme is also essential for NADPH production, glutamine metabolism, and lactate fermentation (16)