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Thus, the development of a therapeutic approach that can alter the outcome of IDD and its associated morbidity will not only lead to significant cost savings for both patients and clinicians but also avoids unnecessary further surgical procedures and unwanted side effects

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High-performance liquid chromatography (HPLC) and enzyme-linked immunosorbent assay (ELISA) were employed to quantify the levels of these key neurotransmitters and neurotrophic factors

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