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ROS and RNS production in physiological conditions is maintained at low levels [25, 26] and used to regulate various physiological functions, including cell signaling, homeostasis, vascular tone, and immune reactions [27]

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doi: 10.1186/s40425-019-0625-x 191 OttPAHu-LieskovanSChmielowskiBGovindanRNaingABhardwajNet al