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In summary, bidirectional DNA methylation regulation outlines the genome-wide epigenetic landscape of malignant progression of thyroid cancer, covering the inactivation of tumor suppressor genes (such as PTEN, RASSF1A) and the abnormal activation of oncogenes (such as TERT, PLAU)

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[DOI] [PubMed] [Google Scholar] 375.Zhou T., Ran J., Xu P., Shen L., He Y., Ye J., Wu L., Gao C