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Preclinically, the overexpression of key downregulated lncRNAs (GAS5 [339], LnRPT [387], MEG3 [385], CASC2 [341], PAHRF [348]) and the suppression of key upregulated lncRNAs (MALAT1 [278], H19 [282, 283, 389], TUG1 [290, 292], AC068039.4 [267], Ang362 [302], HOXA‐AS3 [306], SMILR [323], LINC00963 [390], and PAXIP1‐AS1 [312]) have been shown to alleviate pathological processes during PH development due the maintenance of physiological balance
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[DOI] [PubMed] [Google Scholar] Maruta T, Tanouchi A, Tamoi M, Yabuta Y, Yoshimura K, Ishikawa T, Shigeoka S